Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A study of three polymorphic sites of ADA gene in colon cancer.

Cancer investigation - 1 Dec 2010

Spina C, Saccucci P, Cozzoli E, Bottini E, Gloria-Bottini F

Abstract excerpt

Adenosine inhibits the immune response in tumors. Adenosine deaminase (ADA) controls adenosine level and as ecto-enzyme acts as costimulatory molecule of adenosine receptors and/or CD26. We examined ADA₁, ADA₂, ADA₆ polymorphic sites of ADA gene in 109 subjects with colon cancer from Rome's population and in 246 blood donors as controls from the same population. In colon cancer ADA₁*2/ADA₂*1 haplotype is more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Adenosine
Share to Adenosine Deaminase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Genotype

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 20590444
DOI: 10.3109/07357907.2010.483501

Genes

ADA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A study of three polymorphic sites of ADA gene in colon cancer.PMID 20590444Read ↗

Genetic variability within Adenosine Deaminase gene and uterine leiomyomas.Semantic proximity Read ↗

Carcinogenic effect of adenosine deaminase(ADA) in human tumorsSemantic proximity Read ↗

A study of Adenosine-Deaminase genetic polymorphism in rheumatoid arthritis.Semantic proximity Read ↗

Gender-specific association of ADA genetic polymorphism with human longevity.Semantic proximity Read ↗

A study of three polymorphic sites of the ADA gene in children with type 1 diabetes mellitus.Semantic proximity Read ↗

Clustered charged amino acids of human adenosine deaminase comprise a functional epitope for binding the adenosine deaminase complexing protein CD26/dipeptidyl peptidase IV.Semantic proximity Read ↗

Adenosine deaminase polymorphisms at the protein and DNA levels.Semantic proximity Read ↗

Coronary artery disease. A study of three polymorphic sites of adenosine deaminase gene.Semantic proximity Read ↗

Direct Association of Adenosine Deaminase with a T Cell Activation Antigen, CD26Semantic proximity Read ↗

ADA-2 gene mutation in a Crohn's disease patient without response to therapy.Semantic proximity Read ↗

Further observations on associations between the ADA gene and past malaria morbidity in Sardinia.Semantic proximity Read ↗

Adenosine Kinase Gene Expression in Human Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.