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Article

Human CD26 expression in transgenic mice affects murine T-cell populations and modifies their subset distribution.

Human immunology - 1 Sept 2002

Simeoni Luca, Rufini Alessandro, Moretti Tiziana, Forte Pietro, Aiuti Alessandro, Fantoni Antonio

Abstract excerpt

CD26 is a type II transmembrane glycoprotein with dipeptidyl peptidase (DPPIV) activity, constitutively expressed in different cell types and contributing to T-cell activation by acting as costimulatory molecule. Although data suggest an important role for CD26 within the immune system, the physiologic function of this molecule is still unknown. To investigate the role of CD26 in vivo we have produced transgenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12175726
DOI: 10.1016/s0198-8859(02)00433-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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