Article
Cross-regulatory protein-protein interactions between Hox and Pax transcription factors.
Proceedings of the National Academy of Sciences of the United States of America - 9 Sept 2008
Plaza Serge, Prince Frederic, Adachi Yoshitsugu, Punzo Claudio, Cribbs David L, Gehring Walter J
Abstract excerpt
Homeotic Hox selector genes encode highly conserved transcriptional regulators involved in the differentiation of multicellular organisms. Ectopic expression of the Antennapedia (ANTP) homeodomain protein in Drosophila imaginal discs induces distinct phenotypes, including an antenna-to-leg transf...
Topics
- Animals
- Antennapedia Homeodomain Protein
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Extremities
- Eye Abnormalities
- Gene Expression Regulation, Developmental
- Mutation
- Paired Box Transcription Factors
- Phenotype
- Protein Binding