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Article

Cross-regulatory protein-protein interactions between Hox and Pax transcription factors.

Proceedings of the National Academy of Sciences of the United States of America - 9 Sept 2008

Plaza Serge, Prince Frederic, Adachi Yoshitsugu, Punzo Claudio, Cribbs David L, Gehring Walter J

Abstract excerpt

Homeotic Hox selector genes encode highly conserved transcriptional regulators involved in the differentiation of multicellular organisms. Ectopic expression of the Antennapedia (ANTP) homeodomain protein in Drosophila imaginal discs induces distinct phenotypes, including an antenna-to-leg transformation and eye reduction. We have proposed that the eye loss phenotype is a consequence of a negative...

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Identifiers

PMID: 18755899
DOI: 10.1073/pnas.0806106105
PMCID: PMC2533208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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