Article
DNA fingerprint analysis of Dahl-Iwai salt-sensitive rats (S) and salt-resistant rats (R).
Life sciences - 1 Jan 1994
Yamaguchi S, Umemura S, Iwamoto T, Kobayashi S, Tamura K, Takagi N, Ishii M
Abstract excerpt
Using DNA fingerprint analyses, extensive molecular heterogeneity has been found between spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY), suggesting a doubtful value of simply comparing these rats in the study of the pathogenesis of genetic hypertension. Therefore, we evaluated...
Topics
- Animals
- Base Sequence
- DNA
- DNA Fingerprinting
- Drug Resistance
- Genetic Variation
- Hypertension
- Male
- Molecular Sequence Data
- Rats
- Rats, Inbred Strains
- Sensitivity and Specificity
- Sodium Chloride
