Article
Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells.
Molecular and cellular biology - 1 Jun 1993
Gorski D H, LePage D F, Patel C V, Copeland N G, Jenkins N A, Walsh K
Abstract excerpt
Adult vascular smooth muscle cells dedifferentiate and reenter the cell cycle in response to growth factor stimulation. Here we describe the molecular cloning from vascular smooth muscle, the structure, and the chromosomal location of a diverged homeobox gene, Gax, whose expression is largely con...
Topics
- Animals
- Aorta
- Base Sequence
- Cell Cycle
- Chromosome Mapping
- Cloning, Molecular
- Crosses, Genetic
- DNA
- Female
- G1 Phase
- Gene Library
- Genes, Homeobox
- Genetic Variation
- Homeodomain Proteins
- Humans
- Kinetics
- Male
- Mice