Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.

International journal of radiation biology - 1 Apr 1993

Tauchi H, Nakamura N, Sawada S

Abstract excerpt

Cell cycle dependence for the induction of 6-thioguanine-resistant mutation was investigated using synchronized mouse L5178Y cells after exposure to 4 Gy to 60Co gamma-rays or 1 Gy of 252Cf radiation (fission neutrons). Maximal mutation frequency was observed immediately after release from colcemid block (G2/M phase) after 252Cf radiation, whereas it was 1 h after the release (G1 phase) after 60Co gamma-rays....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cell Line
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to G2 Phase

Share to Gamma Rays

Share to Mitosis

Share to Mutation

Source

Identifiers

PMID: 8096860
DOI: 10.1080/09553009314550631

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.PMID 8096860Read ↗

Cell cycle and LET dependence for radiation-induced mutation: a possible mechanism for reversed dose-rate effect.Semantic proximity Read ↗

Cell cycle-dependent effects of wortmannin on radiation survival and mutation.Semantic proximity Read ↗

X-ray induction of 6-thioguanine-resistant mutants in division arrested, G0/G1 phase Chinese hamster ovary cells.Semantic proximity Read ↗

Induction of hprt mutations in mice after exposure to fission-spectrum neutrons or 60Co gamma rays.Semantic proximity Read ↗

Abrogation of G(2)/M-phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin in TP53 mutant human tumor cells.Semantic proximity Read ↗

[Induction of mutations resistant to 6-thioguanine by fast neutrons in cultured Chinese hamster cells].Semantic proximity Read ↗

Differential response of human fibroblasts to the cytotoxic and mutagenic effects of UV radiation in different phases of the cell cycle.Semantic proximity Read ↗

[Drosophila gene rad201 controls cell cycle arrest in irradiated cells].Semantic proximity Read ↗

Mutation induction by different dose rates of gamma rays in near-diploid mouse cells in plateau- and log-phase culture.Semantic proximity Read ↗

The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation.Semantic proximity Read ↗

Dose-rate effects of neutrons and gamma-rays on the induction of mutation and oncogenic transformation in plateau-phase mouse m5S cells.Semantic proximity Read ↗

Clastogenic effects induced in vitro by CCNU and AMD during G2-phase in bone marrow cells of Wistar rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.