Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.

doi:10.1080/09553009314550631

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Article

Cell cycle dependence for the induction of 6-thioguanine-resistant mutations: G2/M stage is distinctively sensitive to 252Cf neutrons but not to 60Co gamma-rays.

International journal of radiation biology - 1 Apr 1993

Tauchi H, Nakamura N, Sawada S

Abstract excerpt

Cell cycle dependence for the induction of 6-thioguanine-resistant mutation was investigated using synchronized mouse L5178Y cells after exposure to 4 Gy to 60Co gamma-rays or 1 Gy of 252Cf radiation (fission neutrons). Maximal mutation frequency was observed immediately after release from colcem...

Topics

Animals
Californium
Cell Cycle
Cell Line
Cobalt Radioisotopes
Drug Resistance
G2 Phase
Gamma Rays
Mice
Mitosis
Mutation
Neutrons
Thioguanine

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