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Article

Cell cycle and LET dependence for radiation-induced mutation: a possible mechanism for reversed dose-rate effect.

Journal of radiation research - 1 Dec 1999

Tauchi H, Endo S, Eguchi-Kasai K, Furusawa Y, Suzuki M, Matsuura S, Ando K, Nakamura N, Sawada S, Komatsu K

Abstract excerpt

A previous study of the mutagenic action of 252Cf radiation in mouse L5178Y cells showed that the mutation frequency was higher when the dose was chronic rather than acute, which was in sharp contrast to the effects reported for gamma-rays (Nakamura and Sawada, 1988). A subsequent study using synchronized cells revealed that the cells at the G2/M stage were uniquely sensitive to mutation induction by 252Cf...

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Identifiers

PMID: 10804993
DOI: 10.1269/jrr.40.s45

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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