Article
Association between genetic variation at the porphobilinogen deaminase gene and schizophrenia.
Schizophrenia research - 1 Jan 1993
Sanders A R, Rincon-Limas D E, Chakraborty R, Grandchamp B, Hamilton J D, Fann W E, Patel P I
Abstract excerpt
There is growing evidence that some genetic predisposition is important in the etiology of schizophrenia. We have sought to implicate a major gene by performing a candidate gene association study comparing the allele frequencies of seven restriction fragment length polymorphisms (RFLPs) at six lo...
Topics
- Adolescent
- Adult
- Alleles
- Chromosome Mapping
- Deoxyribonucleases, Type II Site-Specific
- Female
- Gene Frequency
- Genetic Carrier Screening
- Genetic Linkage
- Genetic Variation
- Humans
- Hydroxymethylbilane Synthase
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Psychiatric Status Rating Scales
- Schizophrenia