Article
Report from the Maryland Epidemiology Schizophrenia Linkage Study: no evidence for linkage between schizophrenia and a number of candidate and other genomic regions using a complex dominant model.
American journal of medical genetics - 15 Dec 1994
Karayiorgou M, Kasch L, Lasseter V K, Hwang J, Elango R, Bernardini D J, Kimberland M, Babb R, Francomano C A, Wolyniec P S
Abstract excerpt
Our collaborative group has undertaken a linkage study of schizophrenia, using a systematic sample of patients admitted to Maryland hospitals. An initial sample of 39 families, each having two or more affecteds, was available for genotyping candidate genes, candidate regions, and highly polymorphic markers randomly distributed throughout the genome. We used a single complex dominant model (with a disease gene...
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