Article
Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia.
Neuromolecular medicine - 1 Jan 2007
Shinkai Takahiro, De Luca Vincenzo, Hwang Rudi, Müller Daniel J, Lanktree Matthew, Zai Gwyneth, Shaikh Sajid, Wong Gregory, Sicard Tricia, Potapova Natalia, Trakalo Joseph, King Nicole, Matsumoto Chima, Hori Hiroko, Wong Albert H C, Ohmori Osamu, Macciardi Fabio, Nakamura Jun, Kennedy James L
Abstract excerpt
A number of linkage studies have previously implicated the region of chromosome 13q34 in schizophrenia. Chumakov and colleagues (2002) identified a gene complex called G72 (now termed D-amino acid oxidase activator: DAOA)/G30 in this region and performed association analyses of the DAOA/G30 as well as the D-amino-acid oxidase (DAAO) gene with schizophrenia. DAAO oxidizes D-serine, a potent activator of the...
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