Article
Schizophrenia and porphobilinogen deaminase gene polymorphisms: an association study.
Schizophrenia research - 1 Oct 1992
Nimgaonkar V L, Ganguli R, Washington S S, Chakravarti A
Abstract excerpt
A genetic case-control study was conducted in a group of patients with schizophrenia (n = 67; DSM-III) and psychiatrically normal controls matched for ethnicity (n = 84), living in the same geographical area. Using three different DNA polymorphisms of the gene encoding porphobilinogen deaminase (PBGD), a candidate gene for schizophrenia, an association with schizophrenia could not be detected. No significant...
Topics
- Adult
- Alleles
- Chromosome Mapping
- Cohort Studies
- DNA
- Female
- Genotype
- Humans
- Hydroxymethylbilane Synthase
- Male
- Middle Aged
- Polymerase Chain Reaction