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Article

A population-based association study of glutamate decarboxylase 1 as a candidate gene for autism.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2009

Buttenschøn Henriette Nørmølle, Lauritsen Marlene Briciet, El Daoud Agata, Hollegaard Mads, Jorgensen Meta, Tvedegaard Kristine, Hougaard David, Børglum Anders, Thorsen Poul, Mors Ole

Abstract excerpt

Linkage studies, genome-wide scans and screening of possible candidate genes suggest that chromosome 2q31 may harbour one or more susceptibility genes for autism. The glutamate decarboxylase gene 1 (GAD1) located within chromosome 2q31 encodes the enzyme, GAD67, catalyzing the production of gamma-aminobutyric acid (GABA) from glutamate. Numerous independent findings have suggested the GABAergic system to be...

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PMID: 19139806
DOI: 10.1007/s00702-008-0142-4

Genes

GAD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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