Article
Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder.
Molecular psychiatry - 1 Feb 2004
Schumacher J, Jamra R Abon, Freudenberg J, Becker T, Ohlraun S, Otte A C J, Tullius M, Kovalenko S, Bogaert A Van Den, Maier W, Rietschel M, Propping P, Nöthen M M, Cichon S
Abstract excerpt
A recent study has suggested that the brain-expressed genes for G72 and D-amino-acid oxidase (DAAO) exert an influence on susceptibility to schizophrenia. Our aim was to replicate this finding in German schizophrenic patients and to assess whether G72 and DAAO might also contribute to the development of bipolar affective disorder. We genotyped seven single-nucleotide polymorphisms (SNPs) in the G72 gene and three...
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