Article
Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats.
The American journal of physiology - 1 Apr 1996
Meierfrankenfeld B, Abelenda M, Jauker H, Klingenspor M, Kershaw E E, Chua S C, Leibel R L, Schmidt I
Abstract excerpt
To find out whether perinatal differences in energy stores are essential for the phenotypic manifestation of the fa/fa genotype in 16-day-old rats, we investigated Zucker rats (13M) x Brown Norway (BN) hybrids. +/fa and fa/fa hybrids were identified by molecular polymorphisms approximately 1 cM from the fa locus. The fat content of all pups increased rapidly after birth, and differences between +/fa and fa/fa...
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