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Article

Dietary fat and sex modify heterozygote effects of the rat fatty (fa) allele.

The Journal of nutrition - 1 Oct 1996

Maher M A, Banz W J, Truett G E, Zemel M B

Abstract excerpt

Rats carrying one copy of the obesity gene fa may exhibit intermediate phenotypes between lean (+/+) and homozygous mutants (fa/fa). Previous data suggested to us that fa heterozygotes may be more sensitive than wild-type rats to high fat diets. To test this hypothesis, we generated +/+ and fa/+ rats and fed them diets containing 12% or 48% energy as fat for 7 wk. Energy efficiency was significantly greater in...

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Identifiers

PMID: 8857509
DOI: 10.1093/jn/126.10.2487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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