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Article

Role of lipooligosaccharide in virulence of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius for infant rats.

Infection and immunity - 1 Feb 1993

Rubin L G, St Geme J W

Abstract excerpt

Clonally related strains of Haemophilus influenzae biogroup aegyptius have recently been associated with Brazilian purpuric fever (BPF), a fulminant, systemic disease in children. Using an infant rat bacteremia model for BPF, we found that a rat blood-passaged BPF isolate of H. influenzae biogroup aegyptius was more virulent than the original strain was. When compared with the original strain, the animal-passaged...

Topics

Animals
Animals, Newborn
Brazil
Female
Fever
Fimbriae, Bacterial
Haemophilus Infections
Haemophilus influenzae
Lipopolysaccharides
Phenotype
Purpura
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Sprague-Dawley

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 8093694
DOI: 10.1128/iai.61.2.650-655.1993
PMCID: PMC302776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8093694-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Role of lipooligosaccharide in virulence of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius for infant rats.PMID 8093694Read ↗

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