Creation of an isogenic P1-deficient mutant of Haemophilus influenzae biogroup aegyptius.

doi:10.1016/s0378-1119(97)00545-3

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Article

Creation of an isogenic P1-deficient mutant of Haemophilus influenzae biogroup aegyptius.

Gene - 19 Dec 1997

Segada L M, Lesse A J

Abstract excerpt

Haemophilus influenzae biogroup aegyptius, the causative agent of Brazilian purpuric fever (BPF), expresses a heat-modifiable 48 kDa outer membrane protein, P1, which is conserved in most Brazilian case-clone isolates. To study the role of P1 in pathogenesis of BPF we constructed via homologous r...

Topics

Bacterial Outer Membrane Proteins
Cloning, Molecular
Escherichia coli
Gene Deletion
Genes, Bacterial
Genomic Library
Haemophilus influenzae
Mutagenesis, Site-Directed
Phenotype
Suppression, Genetic

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