Article
Frequency of anti-recipient alloreactive helper T-cell precursors in donor blood and graft-versus-host disease after HLA-identical sibling bone-marrow transplantation.
Lancet (London, England) - 23 Jan 1993
Schwarer A P, Jiang Y Z, Brookes P A, Barrett A J, Batchelor J R, Goldman J M, Lechler R I
Abstract excerpt
A substantial proportion of patients undergoing allogeneic bone-marrow transplantation (BMT) develop moderate-to-severe acute graft-versus-host disease (GVHD). Anti-recipient helper (interleukin-2-producing) T-lymphocyte precursors (HTLp) have an important role in the control and amplification of...
Topics
- Adolescent
- Bone Marrow Transplantation
- Child
- Child, Preschool
- England
- Female
- Follow-Up Studies
- Genotype
- Graft vs Host Disease
- HLA Antigens
- Histocompatibility Testing
- Humans
- Incidence
- Indicator Dilution Techniques
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive