Severe acute graft-versus-host disease by HLA-DPB1 disparity in recombinant family of bone marrow transplantation between serologically HLA-identical siblings: an application of the polymerase chain reaction-restriction fragment length polymorphism method.

doi:10.1016/0198-8859(91)90089-r

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Article

Severe acute graft-versus-host disease by HLA-DPB1 disparity in recombinant family of bone marrow transplantation between serologically HLA-identical siblings: an application of the polymerase chain reaction-restriction fragment length polymorphism method.

Human immunology - 1 Dec 1991

Nomura N, Ota M, Kato S, Inoko H, Tsuji K

Abstract excerpt

It has remained to be established that matching of the HLA-DP antigen plays a key role in bone marrow transplantation (BMT), mainly due to the difficulty of the primed lymphocyte test (PLT) method for DP typing. We previously reported an efficient technique for HLA class II genotyping, by digestion of polymerase chain reaction (PCR)-amplified genes with restriction fragment length polymorphisms (RFLP)...

Topics

Acute Disease
Adolescent
Adult
Bone Marrow Transplantation
Child
Child, Preschool
Genotype
Graft Rejection
Graft vs Host Disease
HLA-DP Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DP beta-Chains

Histocompatibility

Histocompatibility Testing

Humans

Infant

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Retrospective Studies

Source

Open in PubMed

Identifiers

PMID: 1686026
DOI: 10.1016/0198-8859(91)90089-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1686026-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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