Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clonal heterogeneity in the progeny of HeLa cells which survive X-irradiation.

International journal of radiation biology - 1 Aug 1994

Brown D C, Trott K R

Abstract excerpt

Clones of HeLa cells that had survived 9 Gy X-rays were investigated for plating efficiency, radiosensitivity, the proportion of giant cells, and chromosome numbers. A significant decrease in plating efficiency was observed that persisted for > 20 population doublings. The reduced plating efficiency was associated with an increased proportion of giant cells in the colonies. There was pronounced clonal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Survival
Share to Chromosomes, Human
Share to Clone Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Radiation

Share to Genetic Variation

Share to HeLa Cells

Share to Radiation Tolerance

Source

Identifiers

PMID: 8089625
DOI: 10.1080/09553009414551051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clonal heterogeneity in the progeny of HeLa cells which survive X-irradiation.PMID 8089625Read ↗

Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome.Semantic proximity Read ↗

Diverse delayed effects in human lymphoblastoid cells surviving exposure to high-LET (56)Fe particles or low-LET (137)Cs gamma radiation.Semantic proximity Read ↗

Ionizing Irradiation Not Only Inactivates Clonogenic Potential in Primary Normal Human Diploid Lens Epithelial Cells but Also Stimulates Cell Proliferation in a Subset of This PopulationSemantic proximity Read ↗

Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation.Semantic proximity Read ↗

Persistently elevated frequency of spontaneous mutations in progeny of CHO clones surviving X-irradiation: association with delayed reproductive death phenotype.Semantic proximity Read ↗

Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells.Semantic proximity Read ↗

A review of human cell radiosensitivity in vitroSemantic proximity Read ↗

Clonogenic Assay: Adherent CellsSemantic proximity Read ↗

Low doses of diagnostic energy X-rays protect against neoplastic transformation in vitroSemantic proximity Read ↗

Effect of multiple irradiation with low doses of gamma-rays on morphological transformation and growth ability of human embryo cells in vitro.Semantic proximity Read ↗

Characteristics of genomic instability in clones of TK6 human lymphoblasts surviving exposure to 56Fe ions.Semantic proximity Read ↗

Multistep nature of X-ray-induced neoplastic transformation in mammalian cells: genetic alterations and instability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.