Article
Characteristics of genomic instability in clones of TK6 human lymphoblasts surviving exposure to 56Fe ions.
Radiation research - 1 Dec 2002
Evans Helen H, Horng Min-Fen, Ricanati Marlene, Diaz-Insua Mireya, Jordan Robert, Schwartz Jeffrey L
Abstract excerpt
Genomic instability in the human lymphoblast cell line TK6 was studied in clones surviving 36 generations after exposure to accelerated 56Fe ions. Clones were assayed for 20 characteristics, including chromosome aberrations, plating efficiency, apoptosis, cell cycle distribution, response to a second irradiation, and mutant frequency at two loci. The primary effect of the 56Fe-ion exposure on the surviving clones...
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