Article
Ponticulin is the major high affinity link between the plasma membrane and the cortical actin network in Dictyostelium.
The Journal of cell biology - 1 Sept 1994
Hitt A L, Hartwig J H, Luna E J
Abstract excerpt
Interactions between the plasma membrane and underlying actin-based cortex have been implicated in membrane organization and stability, the control of cell shape, and various motile processes. To ascertain the function of high affinity actin-membrane associations, we have disrupted by homologous recombination the gene encoding ponticulin, the major high affinity actin-membrane link in Dictyostelium discoideum...
Topics
- Actins
- Animals
- Carrier Proteins
- Cell Membrane
- Dictyostelium
- Freeze Fracturing
- Fungal Proteins
- Microfilament Proteins
- Mutation
- Phagocytosis
- Pinocytosis
