Article
Talin-null cells of Dictyostelium are strongly defective in adhesion to particle and substrate surfaces and slightly impaired in cytokinesis.
The Journal of cell biology - 28 Jul 1997
Niewöhner J, Weber I, Maniak M, Müller-Taubenberger A, Gerisch G
Abstract excerpt
Dictyostelium discoideum contains a full-length homologue of talin, a protein implicated in linkage of the actin system to sites of cell-to-substrate adhesion in fibroblasts and neuronal growth cones. Gene replacement eliminated the talin homologue in Dictyostelium and led to defects in phagocyto...
Topics
- Animals
- Cell Adhesion
- Cell Division
- Cell Movement
- Cell Size
- Chemotactic Factors
- Cyclic AMP
- Dictyostelium
- Edetic Acid
- Escherichia coli
- Mutation
- Phagocytosis
- Salmonella
- Talin