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Article

p53 and RPA Are Sequestered in Viral Replication Centers in the Nuclei of Cells Infected with Human Cytomegalovirus

1 Mar 1998

Abstract excerpt

Previously, we reported that human cytomegalovirus (HCMV) infection of fibroblasts markedly affects p53 and other regulatory proteins and inhibits transit through the cell cycle (F. M. Jault, J.-M. Jault, F. Ruchti, E. A. Fortunato, C. Clark, J. Corbeil, D. D. Richman, and D. H. Spector, J. Virol. 69:6697-6704, 1995). Although the p53 steady-state levels are elevated throughout the infection, evidence suggests...

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Identifiers

PMID: 9499057
DOI: 10.1128/jvi.72.3.2033-2039.1998

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