Article
The cytochrome P450 CYP2D6 allelic variant CYP2D6J and related polymorphisms in a European population.
Pharmacogenetics - 1 Apr 1994
Armstrong M, Fairbrother K, Idle J R, Daly A K
Abstract excerpt
DNA from two subjects showing anomalous CYP2D6 phenotype-genotype relationships was analysed for the presence of new CYP2D6 mutations by single strand conformational polymorphism (SSCP) analysis. One of these subjects was homozygous for polymorphisms in exon 1 and exon 9 previously detected in Or...
Topics
- Alleles
- Asian People
- China
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- DNA Transposable Elements
- Debrisoquin
- England
- Exons
- Gene Frequency
- Homozygote
- Humans
- Mixed Function Oxygenases
- Polymorphism, Genetic
- White People