Article
Combined segregation and linkage analysis of Graves disease with a thyroid autoantibody diathesis.
American journal of human genetics - 1 Sept 1994
Shields D C, Ratanachaiyavong S, McGregor A M, Collins A, Morton N E
Abstract excerpt
Combined segregation and linkage analysis is a powerful technique for modeling linkage to diseases whose etiology is more complex than the effect of a well-described single genetic locus and for investigating the influence of single genes on various aspects of the disease phenotype. Graves disease is familial and is associated with human leukocyte antigen (HLA) allele DR3. Probands with Graves disease, as well as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.