Article
Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA.
The EMBO journal - 1 Sept 1994
Fischer U, Meyer S, Teufel M, Heckel C, Lührmann R, Rautmann G
Abstract excerpt
The Rev trans-activator of human immunodeficiency virus type 1 (HIV-1) is a protein that regulates the simultaneous appearance in the cytoplasm of both spliced and unspliced forms of viral mRNAs from the same viral transcripts by way of recognition of a target sequence termed the Rev-responsive e...
Topics
- Animals
- Base Sequence
- Biological Transport
- Cell Nucleus
- Exons
- Gene Products, rev
- Genes, Synthetic
- HIV-1
- Microinjections
- Molecular Sequence Data
- Mutation
- Oocytes
- Protein Binding
- RNA Precursors
- RNA Splicing
- RNA-Binding Proteins
- Recombinant Proteins
- Sequence Deletion