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Article

Age-dependent selection against hypoxanthine phosphoribosyl transferase-deficient cells in mouse haematopoiesis.

Development (Cambridge, England) - 1 Jul 1993

Samuel K, Clarke A R, Ansell J D, Hooper M L

Abstract excerpt

The basis of a previously observed difference in the level of contribution of hypoxanthine phosphoribosyltransferase-deficient cells between the haematopoietic and non-haematopoietic tissues of chimaeric and heterozygous mice has been clarified by studying two populations of female mice that diff...

Topics

Age Factors
Alleles
Animals
Chimera
Dosage Compensation, Genetic
Female
Hematopoiesis
Hematopoietic Stem Cells
Heterozygote
Hypoxanthine Phosphoribosyltransferase
Isoenzymes
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred Strains

Organ Specificity

Phosphoglycerate Kinase

Selection, Genetic

Source

Identifiers

PMID: 8076522
DOI: 10.1242/dev.118.3.859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8076522-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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