Article
Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation.
Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 1992
Singer-Sam J, Chapman V, LeBon J M, Riggs A D
Abstract excerpt
The preferential inactivation of the paternal X chromosome in extraembryonic cells during early mouse development is an example of parental imprinting, but it has not been studied at the transcriptional level because standard methods of measuring RNA levels do not allow detection of allele-specif...
Topics
- Alleles
- Animals
- Base Sequence
- Blastocyst
- Crosses, Genetic
- Female
- Hypoxanthine Phosphoribosyltransferase
- Male
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phosphoglycerate Kinase
- Polymerase Chain Reaction