Article
Intragenic suppression of integration-defective IS10 transposase mutants.
Genetics - 1 Jun 1994
Junop M S, Hockman D, Haniford D B
Abstract excerpt
IS10 transposase mediates excision and integration reactions in Tn10/IS10 transposition. Mutations in IS10 transposase that specifically block integration have previously been identified; however, the mechanism by which these mutations block integration has not been established. One approach to defining the basis of this block is to identify ways in which the original defect can be corrected. The approach we have...
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