Article
Analysis of MHC class II antigens in Japanese IDDM by a novel HLA-typing method, hybridization protection assay.
Diabetes research and clinical practice - 1 Mar 1994
Maruyama T, Shimada A, Kasuga A, Kasatani T, Ozawa Y, Ishii M, Takei I, Suzuki Y, Kobayashi A, Takeda S
Abstract excerpt
We examined HLA Class II antigens in 116 Japanese IDDM patients [84 typical IDDM (T-IDD); 32 slowly progressive IDDM (S-IDD)] by the hybridization protection assay (HPA) which is a novel HLA typing method based on hybridization of acridinium-ester-labeled DNA probes to amplified DNA. We detected...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Arginine
- Aspartic Acid
- Child
- Child, Preschool
- DNA
- DNA Probes
- Diabetes Mellitus, Type 1
- Female
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Infant
- Infant, Newborn
- Japan