Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Use of the polymerase chain reaction for typing allelic variants of the human HLA-DQA1 by hybridization with oligonucleotide probes, specific for specific alleles].

Molekuliarnaia biologiia - 1 Jan 2000

Ovchinnikov I V, Gavrilov D K, Nosikov V V, Debabov V G

Abstract excerpt

Class II HLA molecules are the most useful markers for susceptibility to different autoimmune diseases, including insulin-dependent diabetes mellitus (IDDM) and rheumatoid arthritis (RA). Polymerase chain reaction and hybridization with a set of allele-specific oligonucleotide have been used for analysis of allelic sequence variation. The analysis of frequencies of HLA-DQA1 alleles among 10 patients of the...

Topics

Alleles
Base Sequence
DNA
Genes, Viral
HLA-DQ Antigens
HLA-DQ alpha-Chains
Humans
Molecular Sequence Data
Nucleic Acid Hybridization
Oligonucleotide Probes
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

T-Phages

Source

Identifiers

PMID: 1753955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1753955-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Use of the polymerase chain reaction for typing allelic variants of the human HLA-DQA1 by hybridization with oligonucleotide probes, specific for specific alleles].PMID 1753955Read ↗

[DNA typing of class I HLA alleles].Semantic proximity Read ↗

Analysis of HLA class II polymorphism using polymerase chain reaction.Semantic proximity Read ↗

HLA-DQB1 typing of north east Italian IDDM patients using amplified DNA, oligonucleotide probes and a rapid DNA-enzyme immunoassay (DEIA).Semantic proximity Read ↗

HLA-DR typing using DNA amplification by the polymerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes.Semantic proximity Read ↗

Techniques used to define human MHC antigens: polymerase chain reaction and oligonucleotide probes.Semantic proximity Read ↗

[Typing for HLA-DR DNA by polymerase chain reaction with sequence-specific primers].Semantic proximity Read ↗

[Analysis of polymorphism of two hypervariable regions of the human genome in the Russian population of Moscow using the polymerase chain reaction].Semantic proximity Read ↗

[HLA-DQ genotyping using a modified technique of PCR-RFLP: application to HLA-DQA1 gene].Semantic proximity Read ↗

[A new method of nonradioactive labelling of oligonucleotides and their use as allele-specific probes for detecting mutations causing beta-thalassemia].Semantic proximity Read ↗

[The polymorphism typing of the HLA-DQ-alpha gene by enzymatic amplification in studying material evidence of biological origin].Semantic proximity Read ↗

[PCR determination of an association between class II HLA and pemphigus vulgaris].Semantic proximity Read ↗

A study on polymerase chain reaction-based HLA DQ alpha locus in Elaziğ, Turkey.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.