Levels of dapsone and pyrimethamine in serum during once-weekly dosing for prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis.

doi:10.1128/AAC.38.5.1197

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Article

Levels of dapsone and pyrimethamine in serum during once-weekly dosing for prophylaxis of Pneumocystis carinii pneumonia and toxoplasmic encephalitis.

Antimicrobial agents and chemotherapy - 1 May 1994

Opravil M, Joos B, Lüthy R

Abstract excerpt

Concentrations of dapsone, monoacetyldapsone, and pyrimethamine were determined in 36 serum samples from human immunodeficiency virus-infected patients on prophylaxis with once-weekly administration of dapsone-pyrimethamine (200 mg of dapsone-75 mg of pyrimethamine). During day 1 after ingestion,...

Topics

Adult
Aged
Dapsone
Drug Interactions
Female
HIV Infections
Humans
Male
Middle Aged
Phenotype
Pneumonia, Pneumocystis
Pyrimethamine
Toxoplasmosis, Cerebral
Zidovudine

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