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Article

Analysis of Current Antifungal Agents and Their Targets within the Pneumocystis carinii Genome

1 Oct 2012

Abstract excerpt

Pneumocystis pneumonia (PCP) remains a leading opportunistic infection in patients with weakened immune systems. The fungus causing the infection belongs to the genus, Pneumocystis, and its members are found in a large variety of mammals. Adaptation to the lung environment of a host with an intact immune system has been a key to its successful survival. Unfortunately, the metabolic strategies used by these fungi...

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PMID: 22934582
DOI: 10.2174/138945012803530107

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