Article
A novel droplet digital polymerase chain reaction for diagnosis of Pneumocystis pneumonia (PCP)-a clinical performance study and survey of sulfamethoxazole-trimethoprim resistant mutations.
The Journal of infection - 1 Dec 2021
Jitmuang Anupop, Nititammaluk Anapat, Boonsong Thitaya, Sarasombath Patsharaporn Techasintana, Sompradeekul Suree, Chayakulkeeree Methee
Abstract excerpt
Objectives To determine the performance of droplet digital polymerase chain reaction (ddPCR) assays in diagnosing Pneumocystis pneumonia (PCP), and to survey the sulfamethoxazole-trimethoprim (SMX-TMP) resistant mutations in our PCP cohort. Methods A prospective study was conducted from January 2017 to June 2018. Adult immunocompromised subjects with pneumonia were enrolled. Bronchoalveolar lavage fluid samples...
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