Article
A cluster of constitutive mutations affecting the C-terminus of the redox-sensitive SoxR transcriptional activator.
Nucleic acids research - 11 Aug 1994
Nunoshiba T, Demple B
Abstract excerpt
Activation of Escherichia coli oxidative stress regulon genes (sodA, zwf, fumC, nfo, etc.) is mediated by a two-stage regulatory system: the redox-sensitive SoxR protein transcriptionally activates the soxS gene, whose product then stimulates transcription of the regulon genes. Previous experimen...
Topics
- Alleles
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Cloning, Molecular
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation
- Oxidation-Reduction
- Polymerase Chain Reaction
- Protein Structure, Secondary
- Sequence Analysis, DNA
- Structure-Activity Relationship
- Trans-Activators
- Transcription Factors