Article
Interactions between gene products involved in divalent cation transport in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 2 Aug 1994
Conklin D S, Culbertson M R, Kung C
Abstract excerpt
The COT1 and ZRC1 genes of Saccharomyces cerevisiae are structurally related dosage-dependent suppressors of metal toxicity. COT1 confers increased tolerance to high levels of cobalt; ZRC1 confers increased tolerance to high levels of zinc. The two genes are not linked and have been mapped; COT1 to chromosome XV and ZRC1 to chromosome XIII. Phenotypes related to metal homeostasis have been examined in strains...
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