Homology-dependent gene silencing in transgenic plants: epistatic silencing loci contain multiple copies of methylated transgenes.

doi:10.1007/BF00285449

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Article

Homology-dependent gene silencing in transgenic plants: epistatic silencing loci contain multiple copies of methylated transgenes.

Molecular & general genetics : MGG - 2 Aug 1994

Matzke A J, Neuhuber F, Park Y D, Ambros P F, Matzke M A

Abstract excerpt

Previous work has shown that two homologous, unlinked transgene loci can interact in plant nuclei, leading to non-reciprocal trans-inactivation and methylation of genes at one locus. Here, we report the structure and methylation of different transgene loci that contain the same construct but are...

Topics

Alleles
Amino Acid Oxidoreductases
Chromosome Mapping
DNA Modification Methylases
Epistasis, Genetic
Gene Expression Regulation
Genes, Plant
Genes, Regulator
In Situ Hybridization
Methylation
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multigene Family

Plants, Genetically Modified

Plants, Toxic

Promoter Regions, Genetic

Sequence Homology, Nucleic Acid

Nicotiana

Source

Open in PubMed

Identifiers

PMID: 8058033
DOI: 10.1007/BF00285449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8058033-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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