Article
Homology-dependent gene silencing in transgenic plants: epistatic silencing loci contain multiple copies of methylated transgenes.
Molecular & general genetics : MGG - 2 Aug 1994
Matzke A J, Neuhuber F, Park Y D, Ambros P F, Matzke M A
Abstract excerpt
Previous work has shown that two homologous, unlinked transgene loci can interact in plant nuclei, leading to non-reciprocal trans-inactivation and methylation of genes at one locus. Here, we report the structure and methylation of different transgene loci that contain the same construct but are variably able to inactivate and methylate a partially homologous, unlinked target locus. Silencing loci comprised...
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