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Article

Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing.

Epigenetics - 1 May 2011

Khaitová Lucie Crhák, Fojtová Miloslava, Křížová Kateřina, Lunerová Jana, Fulneček Jaroslav, Depicker Anna, Kovařík Aleš

Abstract excerpt

It has been well established that trans-acting small RNAs guide promoter methylation leading to its inactivation and gene silencing at the transcriptional level (TGS). Here we addressed the question of the influence of the locus structure and epigenetic modifications of the target locus on its susceptibility for being paramutated by trans-acting small RNA molecules. Silencing was induced by crossing a 35S...

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Source

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Identifiers

PMID: 21521939
DOI: 10.4161/epi.6.5.15764
PMCID: PMC3121974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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