Susceptibility of transgene loci to homology-dependent gene silencing.

doi:10.1007/BF00285450

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Article

Susceptibility of transgene loci to homology-dependent gene silencing.

Molecular & general genetics : MGG - 2 Aug 1994

Neuhuber F, Park Y D, Matzke A J, Matzke M A

Abstract excerpt

Previous work has shown that two unlinked, partially homologous transgene loci can interact in plant nuclei, leading to reversible methylation and inactivation of one transgene locus in the presence of the second. To study whether the chromosomal location of a transgene influences its susceptibility to trans-inactivation, we retransformed four transgenic lines, which contained the same construct (H) integrated in...

Topics

Amino Acid Oxidoreductases
Chloramphenicol O-Acetyltransferase
Cinnamates
Crosses, Genetic
DNA Modification Methylases
Drug Resistance
Epistasis, Genetic
Gene Expression Regulation
Genes, Plant
Homozygote
Hygromycin B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methylation

Phenotype

Phosphotransferases (Alcohol Group Acceptor)

Plants, Genetically Modified

Plants, Toxic

Promoter Regions, Genetic

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 8058034
DOI: 10.1007/BF00285450

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8058034-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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