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Prognostic impact of molecular markers in a series of 220 primary glioblastomas

27 Mar 2006

Abstract excerpt

BACKGROUND: In contrast to oligodendrogliomas, molecular predictors of prognosis have not been consistently found in glioblastomas. However, genetic studies show that glioblastomas consist of several genetic subtypes and raise the possibility that molecular alterations could be predictive of survival. METHODS: A search for loss of heterozygosity (LOH) on chromosome 1p, 9p, 10q, 19q, EGFR (epidermal growth factor...

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PMID: 16568472
DOI: 10.1002/cncr.21819

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