Article
A role for ultraviolet A in solar mutagenesis.
Proceedings of the National Academy of Sciences of the United States of America - 14 Mar 1995
Drobetsky E A, Turcotte J, Châteauneuf A
Abstract excerpt
It is well established that exposure to solar UVB (290-320 nm) gives rise to mutations in oncogenes and tumor suppressor genes that initiate the molecular cascade toward skin cancer. Although UVA (320-400 nm) has also been implicated in multistage photocarcinogenesis, its potential contribution to sunlight mutagenesis remains poorly characterized. We have determined the DNA sequence specificity of mutations...
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