Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994

Nguyen H T, Bodmer R, Abmayr S M, McDermott J C, Spoerel N A

Abstract excerpt

We have identified a mesoderm-specific Drosophila gene, designated D-mef2. The encoded protein contains the MADS- and MEF2-specific domains, which are characteristic of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. D-mef2 RNA is first detectable in the presumptive mesoderm at late cellular blastoderm stage and is expressed in all mesoderm after invagination. Following the dorsal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to DNA-Binding Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Messenger

Share to Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 8052612
DOI: 10.1073/pnas.91.16.7520
PMCID: PMC44433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.PMID 8052612Read ↗

A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila.Semantic proximity Read ↗

The conserved transcription factor Mef2 has multiple roles in adult Drosophila musculature formation.Semantic proximity Read ↗

A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development.Semantic proximity Read ↗

A novel Drosophila, mef2-regulated muscle gene isolated in a subtractive hybridization-based molecular screen using small amounts of zygotic mutant RNA.Semantic proximity Read ↗

Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation.Semantic proximity Read ↗

Different levels, but not different isoforms, of the Drosophila transcription factor DMEF2 affect distinct aspects of muscle differentiation.Semantic proximity Read ↗

Mutations within the conserved MADS box of the D-MEF2 muscle differentiation factor result in a loss of DNA binding ability and lethality in Drosophila.Semantic proximity Read ↗

MEF-2 function is modified by a novel co-repressor, MITR.Semantic proximity Read ↗

A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development.Semantic proximity Read ↗

Alternative requirements for Vestigial, Scalloped, and Dmef2 during muscle differentiation in Drosophila melanogaster.Semantic proximity Read ↗

Identification of the essential protein domains for Mib2 function during the development of the Drosophila larval musculature and adult flight muscles.Semantic proximity Read ↗

Drosophila mind bomb2 is required for maintaining muscle integrity and survival.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.