D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.

doi:10.1073/pnas.91.16.7520

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Article

D-mef2: a Drosophila mesoderm-specific MADS box-containing gene with a biphasic expression profile during embryogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994

Nguyen H T, Bodmer R, Abmayr S M, McDermott J C, Spoerel N A

Abstract excerpt

We have identified a mesoderm-specific Drosophila gene, designated D-mef2. The encoded protein contains the MADS- and MEF2-specific domains, which are characteristic of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. D-mef2 RNA is first detectable in the presumptive mesoderm at late cellular blastoderm stage and is expressed in all mesoderm after invagination. Following the dorsal...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Differentiation
DNA, Recombinant
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Genes, Insect
In Situ Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MEF2 Transcription Factors

Mesoderm

Molecular Sequence Data

Mutation

Myogenic Regulatory Factors

RNA, Messenger

Regulatory Sequences, Nucleic Acid

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 8052612
DOI: 10.1073/pnas.91.16.7520
PMCID: PMC44433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8052612-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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