Article
Expression of the D-MEF2 transcription in the Drosophila brain suggests a role in neuronal cell differentiation.
Oncogene - 18 Apr 1996
Schulz R A, Chromey C, Lu M F, Zhao B, Olson E N
Abstract excerpt
D-MEF2 is a MADS domain transcription factor expressed in the cardiac, somatic, and visceral muscle cell lineages in the Drosophila embryo. Genetic studies have demonstrated that D-mef2 gene function is required for the proper differentiation of all three of these muscle types. We show that D-MEF...
Topics
- Animals
- Animals, Genetically Modified
- Brain
- Cell Differentiation
- Cell Nucleus
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Enhancer Elements, Genetic
- Gene Expression Regulation, Developmental
- Larva
- MEF2 Transcription Factors
- Muscles
- Mutation
- Myogenic Regulatory Factors
- Recombinant Proteins
- Transcription Factors
- beta-Galactosidase