A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development.

doi:10.1016/j.devcel.2006.04.009

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Article

A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development.

Developmental cell - 1 Jun 2006

Sandmann Thomas, Jensen Lars J, Jakobsen Janus S, Karzynski Michal M, Eichenlaub Michael P, Bork Peer, Furlong Eileen E M

Abstract excerpt

Dissecting components of key transcriptional networks is essential for understanding complex developmental processes and phenotypes. Genetic studies have highlighted the role of members of the Mef2 family of transcription factors as essential regulators in myogenesis from flies to man. To understand how these transcription factors control diverse processes in muscle development, we have combined chromatin...

Topics

Animals
Binding Sites
Chromatin Immunoprecipitation
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Enhancer Elements, Genetic
Gene Expression Profiling
Gene Expression Regulation, Developmental
Gene Targeting
Genes, Insect
Kinetics
Models, Biological

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle Development

Mutation

Myogenic Regulatory Factors

Protein Binding

Twist-Related Protein 1

Source

Open in PubMed

Identifiers

PMID: 16740481
DOI: 10.1016/j.devcel.2006.04.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.