Article
Drosophila mind bomb2 is required for maintaining muscle integrity and survival.
The Journal of cell biology - 22 Oct 2007
Nguyen Hanh T, Voza Francesca, Ezzeddine Nader, Frasch Manfred
Abstract excerpt
We report that the Drosophila mind bomb2 (mib2) gene is a novel regulator of muscle development. Unlike its paralogue, mib1, zygotic expression of mib2 is restricted to somatic and visceral muscle progenitors, and their respective differentiated musculatures. We demonstrate that in embryos that lack functional Mib2, muscle detachment is observed beginning in mid stage 15 and progresses rapidly, culminating in...
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