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Article

Are LIF and related cytokines functionally equivalent?

Experimental cell research - 1 Aug 1994

Piquet-Pellorce C, Grey L, Mereau A, Heath J K

Abstract excerpt

Leukemia inhibitory factor (LIF) is structurally related to interleukin-6 (IL-6), oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). Since LIF-deficient mice do not exhibit overt phenotypic effects in cell types known to be targets for LIF action in vitro, we examined the ability of IL-6, OSM, and CNTF to reproduce the effects of LIF in five different bioassays. OSM, CNTF, and LIF are able to promote...

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Source

Identifiers

PMID: 8050491
DOI: 10.1006/excr.1994.1208

Genes

LIF
OSM
CNTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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