Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A pedigree series for mapping disease genes in bipolar affective disorder: sampling, assessment, and analytic considerations.

Psychiatric genetics - 1 Jan 1994

Baron M, Endicott J, Lerer B, Loth J E, Alexander J R, Simon R, Sharpe L, Gibbon M, Hasin D, Lilliston B

Abstract excerpt

A series of 57 extended pedigrees with high density of bipolar affective disorder is described. Ascertainment and diagnostic procedures are documented and simulation studies to assess statistical power are carried out. The pedigrees, obtained in the US and Israel, are comprised of 1508 adult individuals with best estimate consensus diagnoses (12-71 relatives per pedigree), 490 of whom (including 401 sib pairs)...

Topics

Bipolar Disorder
Chromosome Mapping
Cohort Studies
Computer Simulation
Female
Genetic Linkage
Humans
Lod Score
Male
Pedigree
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8049902
DOI: 10.1097/00041444-199421000-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8049902-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pedigree series for mapping disease genes in bipolar affective disorder: sampling, assessment, and analytic considerations.PMID 8049902Read ↗

Genome scans for susceptibility genes in bipolar affective disorder.Semantic proximity Read ↗

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees.Semantic proximity Read ↗

Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms.Semantic proximity Read ↗

The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report.Semantic proximity Read ↗

A genome-wide search for genes predisposing to manic-depression, assuming autosomal dominant inheritance.Semantic proximity Read ↗

Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.Semantic proximity Read ↗

Whole genome linkage analysis in a large Brazilian multigenerational family reveals distinct linkage signals for Bipolar Disorder and DepressionSemantic proximity Read ↗

A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.Semantic proximity Read ↗

Genomic survey of bipolar illness in the NIMH genetics initiative pedigrees: a preliminary report.Semantic proximity Read ↗

Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A linkage study of bipolar illness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.