Article
Cellular characteristics of acute myeloblastic leukemia associated with t(8;21)(q22;q22). The Japanese Cooperative Group of Leukemia/Lymphoma.
Leukemia & lymphoma - 1 Apr 1994
Kita K, Shirakawa S, Kamada N
Abstract excerpt
A large number of AML cases is reviewed in order to clarify biological characteristics of t(8;21) AML cells. The incidence of positivities for stem cell antigens, CD34 and HLA-DR, on blasts in t(8;21) AML is higher in comparison with those in other M2 or M3 categories. Frequent expression of CD34...
Topics
- Acute Disease
- Antigens, Neoplasm
- Biomarkers, Tumor
- Cell Differentiation
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 8
- Genes
- Growth Substances
- Humans
- Leukemia, Myeloid
- Neoplasm Proteins
- Neoplastic Stem Cells
