Article
Phenotypical characteristics of acute myelocytic leukemia associated with the t(8;21)(q22;q22) chromosomal abnormality: frequent expression of immature B-cell antigen CD19 together with stem cell antigen CD34.
Blood - 15 Jul 1992
Kita K, Nakase K, Miwa H, Masuya M, Nishii K, Morita N, Takakura N, Otsuji A, Shirakawa S, Ueda T
Abstract excerpt
Twenty-three acute myelocytic leukemia (AML) patients with t(8;21) chromosomal abnormality, all classified as M2 (French-American-British [FAB] classification), were investigated. Blastic cells from all patients were positive for the stem cell-associated antigens, CD34 and HLA-DR, and the immatur...
Topics
- Adult
- Antigens, CD
- Antigens, CD19
- Antigens, CD20
- Antigens, CD34
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Base Sequence
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 8
- Humans